Overview
The Global PrEP Enrollee Tracker (GPET) is an interactive platform that consolidates, visualises, and analyses data on the number of individuals who have started preexposure prophylaxis (PrEP) for HIV prevention. Launched in 2022 by a coalition of publichealth agencies, NGOs, and research institutions, the tracker provides policymakers, donors, and community advocates with uptodate information on where PrEP is being delivered, who is receiving it, and how programme performance evolves over time.
Why Track PrEP Enrolment?
- Identify gaps: Spot geographic and demographic areas where uptake is low.
- Allocate resources: Direct funding and technical assistance to highneed settings.
- Measure impact: Correlate enrolment trends with HIV incidence data.
- Support advocacy: Provide evidence for scaling up PrEP programmes.
- Enhance accountability: Enable donors and governments to monitor commitments.
Data Sources and Methodology
GPET compiles data from three primary streams:
- National health information systems: Ministries of health submit quarterly reports of PrEP prescriptions and dispensing.
- Implementing partners: NGOs and clinics using the standardized PrEP Monitoring Tool upload enrollee counts via a secure portal.
- Research and surveillance studies: Peerreviewed publications and cohort studies are reviewed annually for supplemental data.
All data are cleaned and harmonised using a common definition of enrollee: a person who has received at least one dose of PrEP medication and is registered in a national or partner database. Duplicates are resolved through unique identifier matching where possible.
Key Metrics Displayed
| Metric | Description | Why It Matters |
|---|---|---|
| Total Enrollees | Cumulative number of individuals who have ever started PrEP. | Shows overall reach of PrEP programmes. |
| Active Users | Enrollees who have refilled medication within the last 90 days. | Indicates continuity of protection. |
| New Enrolments (Quarterly) | Number of firsttime users per quarter. | Tracks growth trends and the impact of outreach. |
| Gender Disaggregation | Male, female, transgender, and nonbinary enrollee counts. | Highlights equity and the need for tailored services. |
| Age Brackets | Enrollee distribution by age (1524, 2534, 3549, 50+). | Guides agespecific messaging and interventions. |
| Key Population Coverage | Proportion of men who have sex with men, sex workers, people who inject drugs, and transgender persons among enrollees. | Ensures programmes reach highrisk groups. |
Regional Summary (2024 Q2)
Data visualisation updated 1May2024.
SubSaharan Africa accounts for 45% of global enrolments, driven by large programmes in South Africa, Kenya, and Uganda. Despite high numbers, activeuser retention is below 60% in several countries, suggesting gaps in followup care.
Latin America and the Caribbean show steady growth, with Brazil and Mexico together contributing 20% of new enrolments in 2024. Adoption among transgender women has risen sharply after targeted community campaigns.
AsiaPacific remains the region with the lowest coverage relative to estimated need. India, Thailand, and Vietnam have expanded pilot projects, but data gaps limit a full assessment.
Eastern Europe & Central Asia have the smallest enrollee base but are notable for high enrolment among people who inject drugs, reflecting effective harmreduction integration.
Challenges in Data Collection and Use
- Inconsistent reporting schedules: Some ministries report annually, creating lag in the tracker.
- Lack of unique identifiers: Duplicate records can inflate enrollee counts.
- Stigma and criminalisation: Key populations may avoid registration, leading to underreporting.
- Variable regimen documentation: Transition from daily oral TDF/FTC to longacting injectables is not yet uniformly captured.
- Data security concerns: Sensitive health information requires robust encryption and access controls.
Future Directions
GPET aims to enhance its utility through several initiatives:
- Realtime dashboards: Integrate API feeds from national electronic health record systems for nearinstant updates.
- Longacting formulation tracking: Separate metrics for injectable cabotegravir to monitor uptake and adherence patterns.
- Geogranular mapping: Move from countrylevel to district or cliniclevel visualisations where data permit.
- Predictive analytics: Use machinelearning models to forecast enrolment trends and identify emerging hotspots.
- Communityled reporting: Enable NGOs to input anonymised data directly, improving coverage of hardtoreach groups.
By 2028 the tracker aspires to become the definitive source for global PrEP monitoring, supporting the World Health Organizations goal of delivering PrEP to at least 3million people at substantial risk of HIV infection.
